{"id":18603,"date":"2015-12-10T23:30:25","date_gmt":"2015-12-10T23:30:25","guid":{"rendered":"http:\/\/mi.pmconsulting.biz\/?page_id=18603"},"modified":"2026-08-27T16:43:30","modified_gmt":"2026-08-27T21:43:30","slug":"asp-1000-2","status":"publish","type":"page","link":"https:\/\/microscopyinnovations.com\/?page_id=18603","title":{"rendered":"mPrep\u2122 ASP\u2122 Automated Specimen Processors"},"content":{"rendered":"<div class=\"wpb-content-wrapper\" id=\"wpb-content-root\"><p>[vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;grid&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; bg_type=&#8221;no_bg&#8221;][vc_column][vc_row_inner row_type=&#8221;row&#8221; type=&#8221;full_width&#8221; text_align=&#8221;left&#8221; css_animation=&#8221;&#8221;][vc_column_inner width=&#8221;1\/2&#8243;][vc_empty_space height=&#8221;60px&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;]<br \/>\n[\/vc_column_inner][\/vc_row_inner][vc_row_inner row_type=&#8221;row&#8221; type=&#8221;full_width&#8221; text_align=&#8221;left&#8221; css_animation=&#8221;&#8221;][vc_column_inner][vc_column_text]<\/p>\n<h1>mPrep\u2122 ASP\u2122 Automated Specimen Processors<\/h1>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;20px&#8221;][\/vc_column_inner][\/vc_row_inner][vc_row_inner row_type=&#8221;row&#8221; type=&#8221;full_width&#8221; text_align=&#8221;left&#8221; css_animation=&#8221;&#8221;][vc_column_inner width=&#8221;1\/2&#8243;][vc_column_text]mPrep\u2122 ASP\u2122 instruments automate and accelerate biological sample preparation for the highest-quality TEM and 3D volume EM (vEM), including serial block, focused ion beam and array tomography SEM.<\/p>\n<p>Every mPrep ASP is purpose built for aggressive EM solvents and oxidizing reagents. The ASP-2500 has all the features of the ASP-1500 with the added benefit of temperature controlled reagents.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>One ASP instrument<\/strong> prepares TEM and vEM specimens including tissues, cell pellets, organoids and cell adhesion substrates (e.g. coverslips), and does on-grid and pre-embedding immuno-gold labeling.<\/p>\n<p><strong>Specimen counts vary?<\/strong>\u00a0 Efficiently prepare just one specimen, or prepare up to 128 TEM or up to 64 vEM specimens at one time.<\/p>\n<p><strong>Complicated protocols? <\/strong>\u00a0Simultaneously prepare specimens or grids with up to 8 different protocols, with up to 72 reagent steps and 576 different reagents, and even more.<\/p>\n<p><strong>Expensive reagents? \u00a0<\/strong>No problem. Requires only ~40 microliters per reagent step.<\/p>\n<p><strong>Identical processing<\/strong> with unique microfluidic-directed-flow agitation for consistent and efficient reagent infiltration.<\/p>\n<p><strong>Time, hands-on effort, and reagent efficiency. <\/strong>See how 4 core labs use ASPs for efficient TEM and vEM workflows: <a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2024\/02\/Goodman_MicroToday-Jan-2024_Create-Efficient-Workflows.pdf\" target=\"_blank\" rel=\"noopener\">Microscopy Today 2024<\/a>.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong>mPrep ASPs accelerate TEM and vEM preparation from days to hours:<\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2024\/08\/Flint_Efficient-Clinical-TEM-Workflow-Auto-Specimen-Processing_MM2024_Microsc_Microanal_30_847_ProcPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">TEM &#8211; Prepare up to 128 clinical renal biopsy or muscle core segments in ~3 ho<\/a><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2019\/08\/Strader-automated_Prep_Core-Needle_Biopsy_Specimens_TEM_Microsc-Microanal-25-2019_AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">urs -Winner 2024 Diatome Poster Award<\/a><\/li>\n<li>TEM &#8211; Prepare muscle in 133 minutes &#8211; <a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2017\/04\/AN602-Automated-Prep-Muscle-ASP.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Applications Note<\/a> and\u00a0<a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2018\/04\/Tetri-LJ-et-al-2018-Front-Physiol-9.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Publication<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2019\/03\/AN-603_RapidParallelTissueProcessing_rev1b_PressQuality.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">TEM &#8211; Liver &#8211; in 133 minutes<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2016\/08\/McClain-Bringing-Speed-Automation-Together-with-ASP-1000-Microsc-Microanal-22-2016-PDP-49-AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">TEM &#8211; Planaria &#8211; in 3 hours, instead of 7 days<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2017\/08\/Stewart-Preparing-LR-White-Embedded-Tissue-mPreps-Microsc-Microanal-23-2017-PDP-56-AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">TEM &#8211; LR White acrylic prep for immuno-labeling &#8211; in 45 minutes<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2018\/08\/AN-604_AgarEmbeddedCellsForTEM_rev1_FINAL_WebQuality.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">TEM &#8211; Agar enrobed yeast &#8211; in 1.5 hours\u00a0<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0091679X23000092?via%3Dihub\" target=\"_blank\" rel=\"noopener\">vEM &#8211; Serial block face, FIB-SEM, and Array Tomography prep of brain and breast cancer in 7 hours &#8211; Methods in Cell Biology volume 177<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2022\/08\/2020-Stempinski_Auto-Sample-vEM-Breast-Cancer-Model_Microsc-Microanal-28-2022-1370-poster.pdf\" target=\"_blank\" rel=\"noopener\">vEM &#8211; FIB-SEM &amp; Serial block face &#8211; breast cancer specimens in 5 hours instead 2.5 days.<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2020\/08\/Benson_serial_blockface_sem_brain_ASP_MM2020_534_abstractposter.pdf\" target=\"_blank\" rel=\"noopener\">vEM &#8211; Serial block face &#8211; brain prepared in a day &#8211; Winner 2020 Diatome Poster Award<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2019\/08\/Goodman-Postnatal_Hyperoxia_Cardiac_Muscle_3D_SEM_Automated_Prep_Micro-Microanal-25-2019-PDP-46_abstractposter.pdf\" target=\"_blank\" rel=\"noopener\">vEM &#8211; Serial block face &#8211; heart in 8 hours<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2017\/08\/McClain-Rapid-Automated-enbloc-SEM-Microsc-Microanal-23-2017-PDP-59-AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener\">vEM &#8211; Serial block face &#8211; planaria in less than a day &#8211; Winner 2017 Diatome Poster Award<\/a><\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_empty_space][vc_column_text]<strong>Stop babysitting reagent exchanges!<\/strong><\/p>\n<ul>\n<li>TEM specimen fixation, en bloc staining, dehydration, and embedding<\/li>\n<li>Immunolabeling &#8211; <a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2018\/08\/Marques-Optimization_automated_immuno_EM_pre_post_embedding_Micro-Microanal-24-2018_AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">On grid and pre-embedding (en bloc)<\/a><\/li>\n<li>vEM specimen\u00a0fixation, staining, dehydration, and embedding<\/li>\n<li>SEM specimen fixation and dehydration<\/li>\n<li>Easy set-up and clean-up.<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_empty_space][vc_column_text]<\/p>\n<h2><\/h2>\n<h2><strong>Easy\u00a0Intuitive Protocol Creation<\/strong><\/h2>\n<ul>\n<li>Pre-written protocols for TEM and vEM<\/li>\n<li>Create new protocols or customize existing protocols &#8211; specify reagent, reaction time, agitation, and reagent temperature (ASP-2000 and ASP-2500)<\/li>\n<li>Two-tiered access: Operator and Developer<\/li>\n<li>Precise and efficient protocols with greater reproducibly than humanly possible.<\/li>\n<li>Protocols are easily shared with any ASP-equipped lab with any ASP model.<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_empty_space][vc_single_image onclick=&#8221;custom_link&#8221; image=&#8221;20800&#8243; img_size=&#8221;medium&#8221; css=&#8221;.vc_custom_1787342638633{border-radius: 2px !important;}&#8221; qode_css_animation=&#8221;&#8221; link=&#8221;url:https%3A%2F%2Fmicroscopyinnovations.com%2Fwp-content%2Fuploads%2F2023%2F04%2FASP-Brochure_web_030123.pdf|target:_blank&#8221; img_link_target=&#8221;_blank&#8221;][vc_empty_space][vc_column_text][\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/12&#8243;]<br \/>\n[\/vc_column_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;19644&#8243; img_size=&#8221;325&#215;400&#8243; style=&#8221;vc_box_border&#8221; qode_css_animation=&#8221;&#8221;][vc_empty_space height=&#8221;20px&#8221;][vc_single_image image=&#8221;19830&#8243; img_size=&#8221;325&#215;405&#8243; style=&#8221;vc_box_border&#8221; qode_css_animation=&#8221;&#8221;][vc_empty_space height=&#8221;20px&#8221;][vc_single_image image=&#8221;19596&#8243; img_size=&#8221;325&#215;405&#8243; style=&#8221;vc_box_border&#8221; qode_css_animation=&#8221;&#8221;][vc_column_text][\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_empty_space][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;grid&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column]<div id=\"advanced-tabs-desc-wrap-2699\" class=\"ult_tabs \" style=\" \" data-tabsstyle=\"style1\"\n data-titlebg=\"#e7ecea\" data-titlecolor=\"#74777b\" data-fullheight=\"off\"\n data-titlehoverbg=\"#d4d8d6\" data-titlehovercolor=\"#ffffff\"\n data-rotatetabs=\"0\" data-responsivemode=\"Both\" data-animation=\"Slide\"\ndata-activetitle=\"#ffffff\" data-activeicon=\"\" data-activebg=\"#c74699\"  data-respmode=\"Tabs\" data-respwidth=\"400\" data-scroll = \"on\" data-activeindex=\"1\"><ul id=advanced-tabs-wrap-1370 class=\"ult_tabmenu style1 Style_6\" style=\"color:transparent;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;border-bottom-width:0px;\"><li class=\"ult_tab_li ult_tab_style_6 \" data-iconcolor=\"#74777b\" data-iconhover=\"#ffffff\" style=\"background-color:#e7ecea;border-top-left-radius:8px;\">\n\t\t\t\t\t<a href=\"#1561995603434-115620146576341562081400189\"  id=\"1561995603434-115620146576341562081400189\"  style=\"color:#74777b;;border-color:#333333;   \" class=\"ult_a ult_tab_style_6 \">\n\t\t\t\t\t     <span class=\"ult_tab_main Both \">\n\t\t\t\t\t \t\t <span class=\"ult_tab_section\">\n\t\t\t\t\t   \t\t\t<span  data-ultimate-target='#advanced-tabs-wrap-1370 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text no_icon ult_tab_display_text ult-responsive\" style=\"font-weight:bold;;\">ASP product info<\/span>\n\t\t\t\t\t   \t\t<\/span>\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/li><li class=\"ult_tab_li ult_tab_style_6 \" data-iconcolor=\"#74777b\" data-iconhover=\"#ffffff\" style=\"background-color:#e7ecea;\">\n\t\t\t\t\t<a href=\"#1561995603501-115620146576341562081400189\"  id=\"1561995603501-115620146576341562081400189\"  style=\"color:#74777b;;border-color:#333333;   \" class=\"ult_a ult_tab_style_6 \">\n\t\t\t\t\t     <span class=\"ult_tab_main Both \">\n\t\t\t\t\t \t\t <span class=\"ult_tab_section\">\n\t\t\t\t\t   \t\t\t<span  data-ultimate-target='#advanced-tabs-wrap-1370 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text no_icon ult_tab_display_text ult-responsive\" style=\"font-weight:bold;;\">System components<\/span>\n\t\t\t\t\t   \t\t<\/span>\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/li><li class=\"ult_tab_li ult_tab_style_6 \" data-iconcolor=\"#74777b\" data-iconhover=\"#ffffff\" style=\"background-color:#e7ecea;\">\n\t\t\t\t\t<a href=\"#1562004296515-2-615620146576341562081400189\"  id=\"1562004296515-2-615620146576341562081400189\"  style=\"color:#74777b;;border-color:#333333;   \" class=\"ult_a ult_tab_style_6 \">\n\t\t\t\t\t     <span class=\"ult_tab_main Both \">\n\t\t\t\t\t \t\t <span class=\"ult_tab_section\">\n\t\t\t\t\t   \t\t\t<span  data-ultimate-target='#advanced-tabs-wrap-1370 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text no_icon ult_tab_display_text ult-responsive\" style=\"font-weight:bold;;\">Applications<\/span>\n\t\t\t\t\t   \t\t<\/span>\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/li><li class=\"ult_tab_li ult_tab_style_6 \" data-iconcolor=\"#74777b\" data-iconhover=\"#ffffff\" style=\"background-color:#e7ecea;border-top-right-radius:8px;\">\n\t\t\t\t\t<a href=\"#1562010045120-4-815620146576341562081400189\"  id=\"1562010045120-4-815620146576341562081400189\"  style=\"color:#74777b;;border-color:#333333;   \" class=\"ult_a ult_tab_style_6 \">\n\t\t\t\t\t     <span class=\"ult_tab_main Both \">\n\t\t\t\t\t \t\t <span class=\"ult_tab_section\">\n\t\t\t\t\t   \t\t\t<span  data-ultimate-target='#advanced-tabs-wrap-1370 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text no_icon ult_tab_display_text ult-responsive\" style=\"font-weight:bold;;\">Purchase<\/span>\n\t\t\t\t\t   \t\t<\/span>\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/li><\/ul><div  data-ultimate-target='#advanced-tabs-desc-wrap-2699 .ult_tabcontent .ult_tab_min_contain  p'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' class=\"ult_tabcontent ult-responsive style1\" style=\"color:#74777b;\"><div class=\"ult_tab_min_contain \" >\n\t\t\t<div  class=\"ult_tabitemname\"  >\n\t\t\t\t[vc_empty_space height=&#8221;20px&#8221;][vc_column_text css=&#8221;.vc_custom_1665436913853{margin-top: 40px !important;margin-bottom: 20px !important;}&#8221;]<\/p>\n<h2>Using ASP processors<\/h2>\n<p>[\/vc_column_text][vc_column_text]1. Select a protocol (or easily create a new protocol)<\/p>\n<p>2. \u00a0Attach mPrep capsules with loaded specimens or grids<\/p>\n<p>3. \u00a0Place reagents in microwell plates on the ASP tray. Optionally seal reagent plates with disposable covers to cut air exposure and prevent evaporation<\/p>\n<p>4. \u00a0Press\u00a0<strong>START<\/strong>. \u00a0The ASP does the rest:<\/p>\n<p style=\"padding-left: 30px;\">&#8211; mPrep capsules move from reagent to reagent<\/p>\n<p style=\"padding-left: 30px;\">&#8211; Reagents are drawn into mPrep capsules for the specified time<\/p>\n<p style=\"padding-left: 30px;\">&#8211; Agitation flows reagent in and out of capsules for excellent mixing<\/p>\n<p style=\"padding-left: 30px;\">&#8211; mPrep capsules punch through optional reagent covers. Reagents are always fresh<\/p>\n<p>5. \u00a0When the protocol is completed, remove capsules from the ASP:<\/p>\n<p style=\"padding-left: 30px;\">&#8211; For TEM and vEM embedding there is no messy handling of specimens in resin. Eight resin-filled mPrep\/s capsules are simply transferred to the oven to cure the resin<\/p>\n<p style=\"padding-left: 30px;\">&#8211; For grids, mPrep\/g capsules are removed and stored in an mPrep Capsule Grid box. No tedious handling of grids<\/p>\n<p style=\"padding-left: 30px;\">&#8211; For SEM preparation simply transfer capsules directly to the CPD holder with no direct specimen handling.<\/p>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;30px&#8221;][vc_column_text css=&#8221;.vc_custom_1444249017440{margin-top: 40px !important;margin-bottom: 20px !important;}&#8221;]<\/p>\n<h2>Product Description<\/h2>\n<p>[\/vc_column_text][vc_column_text]<\/p>\n<h3>Capacity<\/h3>\n<ul>\n<li>1 to 128 tissue biopsy pieces or other specimens\u00a0for TEM<\/li>\n<li>1 to 64 tissue pieces or other specimens for vEM<\/li>\n<li>1 to 32 TEM grids<\/li>\n<li>8 reagent delivery channels enable simultaneous preparation with 1 to 8 different reagent sequences<\/li>\n<li>Up to 8 coverslips for TEM or vEM fixation, staining and embedding<\/li>\n<li>Unlimited protocol steps<\/li>\n<li>Up to 72 reagent\u00a0operations on the deck at a time<\/li>\n<li>Up to 576 reagents using 96-well microwell plates to hold reagents<\/li>\n<\/ul>\n<h3><\/h3>\n<p>&nbsp;<\/p>\n<h3>Includes<\/h3>\n<ul>\n<li>Automation platform with proven track record for reliability<\/li>\n<li>Eight channel head<\/li>\n<li>Pump module<\/li>\n<li>Integrated removable fume enclosure<\/li>\n<li>Microwell tray accommodates up to 6 standard 96-well or 12-well reservoirs<\/li>\n<li>Laptop Controller with multiple preinstalled protocols<\/li>\n<\/ul>\n<h3><\/h3>\n<p>&nbsp;<\/p>\n<h3>Installation requirements<\/h3>\n<ul>\n<li>120-130 VAC 60 cycle, 220 VAC 50 cycle or 100 VAC 50\/100 cycle. \u00a0Inquire for details.<\/li>\n<li>ASPs should be installed to vent into a fume hood for safety with electron microscopy reagents<\/li>\n<li>Required space for base unit including integrated cover: 48 cm wide x 61 cm deep x 64 cm high (19 x 24 x 25 inch)<\/li>\n<li>Required space for pump module adjacent to base unit: 21 cm wide x 17 cm deep x 31 cm high (8 x 7 x 12 inch)<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2026\/07\/ASP-2500-Brochure-2026-web.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Download the ASP brochure<\/a><\/h2>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;60px&#8221;]\n\t\t\t<\/div>\n\t\t\t<div  class=\"ult_tabitemname\"  >\n\t\t\t\t[vc_empty_space height=&#8221;20px&#8221;][vc_row_inner row_type=&#8221;row&#8221; type=&#8221;full_width&#8221; text_align=&#8221;left&#8221; css_animation=&#8221;&#8221;][vc_column_inner width=&#8221;1\/2&#8243;][vc_column_text]<\/p>\n<h2>Required<\/h2>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;20px&#8221;][vc_column_text]<strong>mPrep\/g capsules <\/strong>to prepare TEM grids<\/p>\n<p><strong>mPrep\/s capsules<\/strong>\u00a0to prepare specimens<\/p>\n<p><strong>mPrep\/f couplers<\/strong> to prevent introducing damaging reagents into ASP<\/p>\n<p><strong>mPrep\/Bench\u00a0<\/strong>to\u00a0transfer resin-filled mPrep\/s capsules to oven for resin curing<\/p>\n<p><strong>Microwell plates<\/strong> to hold reagents. Use either 96-well or 12-well[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_column_text]<\/p>\n<h2>Recommended<\/h2>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;20px&#8221;][vc_column_text]<strong>mPrep CPD holder<\/strong>\u00a0for use with critical point dryers and some cryo-preparation applications<\/p>\n<p><b>Microwell plate covers <\/b>to cover and seal reagents in microwell plates<b>\u00a0<\/b>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner]\n\t\t\t<\/div>\n\t\t\t<div  class=\"ult_tabitemname\"  >\n\t\t\t\t[vc_empty_space height=&#8221;20px&#8221;][vc_column_text]<\/p>\n<h3>ASPs can be used for the full range of\u00a0specimen and grid preparation applications.\u00a0Please refer to TEM, SEM and vEM, and Materials Applications.<\/h3>\n<p>&nbsp;<\/p>\n<h3>See how the ASP-1000 and ASP-2000 have been used for these applications:<\/h3>\n<ul>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2017\/02\/AN601-Fast-Automated-Tissue-Processing-Kidney-with-ASP-1000.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Preparing kidney for TEM in 45 minutes from postfix to oven curing<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2019\/08\/Strader-automated_Prep_Core-Needle_Biopsy_Specimens_TEM_Microsc-Microanal-25-2019_AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Preparing core needle kidney biopsies for TEM including en bloc uranyl acid staining in 2 hours prior to resin curing<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2017\/04\/AN602-Automated-Prep-Muscle-ASP.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Processing oriented mammalian muscle for TEM in 2 hours from postfix to oven curing<\/a><\/li>\n<li>Serial block face specimen preparation of <a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2019\/08\/Goodman-Rapid_Auto_Prep_SBEM_Microsc-Microanal-25-2019_AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">brain<\/a>, <a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2019\/08\/Goodman-Postnatal_Hyperoxia_Cardiac_Muscle_3D_SEM_Automated_Prep_Micro-Microanal-25-2019-PDP-46_abstractposter.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">heart<\/a>, and <a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2019\/08\/McClain-Automated_Heavy_Metal_Tissue_Staining_Serial_Block_Face_Imaging_ASP-1000_Micro-Microanal-25-2019-PDP-52-Abstract.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">planeria <\/a>in about one day, instead of a week<\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2016\/08\/McClain-Bringing-Speed-Automation-Together-with-ASP-1000-Microsc-Microanal-22-2016-PDP-49-AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Rapid automated preparation of Planarian worm tissue for TEM in 3 hours<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2018\/08\/Marques-Optimization_automated_immuno_EM_pre_post_embedding_Micro-Microanal-24-2018_AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Fully automated immunogold pre-embedding and on grid labeling<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2017\/08\/Stewart-Preparing-LR-White-Embedded-Tissue-mPreps-Microsc-Microanal-23-2017-PDP-56-AbstractPoster.pdf\">Fixation and embedding in LR White resin in 45 minutes<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2017\/09\/AN-603-Rapid-Parallel-Liver-ASP.pdf\">Liver reliably and consistently prepared for TEM in just 133 minutes prior to resin curing<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2017\/08\/McClain-Rapid-Automated-enbloc-SEM-Microsc-Microanal-23-2017-PDP-59-AbstractPoster.pdf\">Planaria fixed, <em>en bloc<\/em> stained and ready for for 3D SEM block face imaging in 1.5 days<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2016\/08\/Vierrether-Nano-Particle-TEM-Sample-Prep-Primer-Microsc-Microanal-22-2016-1914-AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Automated preparation of nano-particle TEM specimens.<\/a><\/li>\n<\/ul>\n<p>[\/vc_column_text]\n\t\t\t<\/div>\n\t\t\t<div  class=\"ult_tabitemname\"  >\n\t\t\t\t[vc_empty_space height=&#8221;20px&#8221;][vc_row_inner row_type=&#8221;row&#8221; type=&#8221;full_width&#8221; text_align=&#8221;left&#8221; css_animation=&#8221;&#8221;][vc_column_inner][vc_column_text]<!- View not found ->[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_column_text]<\/p>\n<p style=\"text-align: center;\">For a complete listing of mPrep products, click <a href=\"\/purchase\/\">Purchase<\/a>.<\/p>\n<p>[\/vc_column_text]\n\t\t\t<\/div><\/div><\/div><\/div><div class=\"ult_acord advanced-tabs-desc-wrap-2699\">\n   <div class=\"ult-tabto-accordion \" style=\"width:;\"\n    data-titlecolor=\"#74777b\"  data-titlebg=\"#e7ecea\"\n     data-titlehoverbg=\"#d4d8d6\" data-titlehovercolor=\"#ffffff\" data-animation=\"Slide\"\n     data-activetitle=\"#ffffff\" data-activeicon=\"\" data-activebg=\"#c74699\" data-scroll = \"on\" data-activeindex=\"1\" >\n     <dl><dt class=\"\">\n\t        \t<a class=\"ult-tabto-actitle withBorder ult_a \" id=\"1561995603434-115620146576341562081400189\" style=\"color:#74777b;border-color:#333333;;background-color:#e7ecea;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;\" href=\"#1561995603434-115620146576341562081400189\">\n\t        \t\t<i class=\"accordion-icon\"><\/i>\n\t        \t\t\t<span class=\"ult_tab_main ult_ac_main ult_noacordicnBoth\">\n\n\t\t\t\t\t\t<span  data-ultimate-target='#advanced-tabs-wrap-1370 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text no_icon ult_acordian-text ult-responsive\" style=\"font-weight:bold;;color:inherit \" >ASP product info<\/span>\n\t\t\t\t\t\t<\/span><\/a><\/dt>\n\t            \t\t<dd class=\"ult-tabto-accordionItem ult-tabto-accolapsed\">\n\t\t\t\t            <div class=\"ult-tabto-acontent\" style=\"color:#74777b;\">\n\t\t\t\t               [vc_empty_space height=&#8221;20px&#8221;][vc_column_text css=&#8221;.vc_custom_1665436913853{margin-top: 40px !important;margin-bottom: 20px !important;}&#8221;]<\/p>\n<h2>Using ASP processors<\/h2>\n<p>[\/vc_column_text][vc_column_text]1. Select a protocol (or easily create a new protocol)<\/p>\n<p>2. \u00a0Attach mPrep capsules with loaded specimens or grids<\/p>\n<p>3. \u00a0Place reagents in microwell plates on the ASP tray. Optionally seal reagent plates with disposable covers to cut air exposure and prevent evaporation<\/p>\n<p>4. \u00a0Press\u00a0<strong>START<\/strong>. \u00a0The ASP does the rest:<\/p>\n<p style=\"padding-left: 30px;\">&#8211; mPrep capsules move from reagent to reagent<\/p>\n<p style=\"padding-left: 30px;\">&#8211; Reagents are drawn into mPrep capsules for the specified time<\/p>\n<p style=\"padding-left: 30px;\">&#8211; Agitation flows reagent in and out of capsules for excellent mixing<\/p>\n<p style=\"padding-left: 30px;\">&#8211; mPrep capsules punch through optional reagent covers. Reagents are always fresh<\/p>\n<p>5. \u00a0When the protocol is completed, remove capsules from the ASP:<\/p>\n<p style=\"padding-left: 30px;\">&#8211; For TEM and vEM embedding there is no messy handling of specimens in resin. Eight resin-filled mPrep\/s capsules are simply transferred to the oven to cure the resin<\/p>\n<p style=\"padding-left: 30px;\">&#8211; For grids, mPrep\/g capsules are removed and stored in an mPrep Capsule Grid box. No tedious handling of grids<\/p>\n<p style=\"padding-left: 30px;\">&#8211; For SEM preparation simply transfer capsules directly to the CPD holder with no direct specimen handling.<\/p>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;30px&#8221;][vc_column_text css=&#8221;.vc_custom_1444249017440{margin-top: 40px !important;margin-bottom: 20px !important;}&#8221;]<\/p>\n<h2>Product Description<\/h2>\n<p>[\/vc_column_text][vc_column_text]<\/p>\n<h3>Capacity<\/h3>\n<ul>\n<li>1 to 128 tissue biopsy pieces or other specimens\u00a0for TEM<\/li>\n<li>1 to 64 tissue pieces or other specimens for vEM<\/li>\n<li>1 to 32 TEM grids<\/li>\n<li>8 reagent delivery channels enable simultaneous preparation with 1 to 8 different reagent sequences<\/li>\n<li>Up to 8 coverslips for TEM or vEM fixation, staining and embedding<\/li>\n<li>Unlimited protocol steps<\/li>\n<li>Up to 72 reagent\u00a0operations on the deck at a time<\/li>\n<li>Up to 576 reagents using 96-well microwell plates to hold reagents<\/li>\n<\/ul>\n<h3><\/h3>\n<p>&nbsp;<\/p>\n<h3>Includes<\/h3>\n<ul>\n<li>Automation platform with proven track record for reliability<\/li>\n<li>Eight channel head<\/li>\n<li>Pump module<\/li>\n<li>Integrated removable fume enclosure<\/li>\n<li>Microwell tray accommodates up to 6 standard 96-well or 12-well reservoirs<\/li>\n<li>Laptop Controller with multiple preinstalled protocols<\/li>\n<\/ul>\n<h3><\/h3>\n<p>&nbsp;<\/p>\n<h3>Installation requirements<\/h3>\n<ul>\n<li>120-130 VAC 60 cycle, 220 VAC 50 cycle or 100 VAC 50\/100 cycle. \u00a0Inquire for details.<\/li>\n<li>ASPs should be installed to vent into a fume hood for safety with electron microscopy reagents<\/li>\n<li>Required space for base unit including integrated cover: 48 cm wide x 61 cm deep x 64 cm high (19 x 24 x 25 inch)<\/li>\n<li>Required space for pump module adjacent to base unit: 21 cm wide x 17 cm deep x 31 cm high (8 x 7 x 12 inch)<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2026\/07\/ASP-2500-Brochure-2026-web.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Download the ASP brochure<\/a><\/h2>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;60px&#8221;]\n\t\t\t\t            <\/div>\n\t        \t\t\t<\/dd><dt class=\"\">\n\t        \t<a class=\"ult-tabto-actitle withBorder ult_a \" id=\"1561995603501-115620146576341562081400189\" style=\"color:#74777b;border-color:#333333;;background-color:#e7ecea;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;\" href=\"#1561995603501-115620146576341562081400189\">\n\t        \t\t<i class=\"accordion-icon\"><\/i>\n\t        \t\t\t<span class=\"ult_tab_main ult_ac_main ult_noacordicnBoth\">\n\n\t\t\t\t\t\t<span  data-ultimate-target='#advanced-tabs-wrap-1370 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text no_icon ult_acordian-text ult-responsive\" style=\"font-weight:bold;;color:inherit \" >System components<\/span>\n\t\t\t\t\t\t<\/span><\/a><\/dt>\n\t            \t\t<dd class=\"ult-tabto-accordionItem ult-tabto-accolapsed\">\n\t\t\t\t            <div class=\"ult-tabto-acontent\" style=\"color:#74777b;\">\n\t\t\t\t               [vc_empty_space height=&#8221;20px&#8221;][vc_row_inner row_type=&#8221;row&#8221; type=&#8221;full_width&#8221; text_align=&#8221;left&#8221; css_animation=&#8221;&#8221;][vc_column_inner width=&#8221;1\/2&#8243;][vc_column_text]<\/p>\n<h2>Required<\/h2>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;20px&#8221;][vc_column_text]<strong>mPrep\/g capsules <\/strong>to prepare TEM grids<\/p>\n<p><strong>mPrep\/s capsules<\/strong>\u00a0to prepare specimens<\/p>\n<p><strong>mPrep\/f couplers<\/strong> to prevent introducing damaging reagents into ASP<\/p>\n<p><strong>mPrep\/Bench\u00a0<\/strong>to\u00a0transfer resin-filled mPrep\/s capsules to oven for resin curing<\/p>\n<p><strong>Microwell plates<\/strong> to hold reagents. Use either 96-well or 12-well[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_column_text]<\/p>\n<h2>Recommended<\/h2>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;20px&#8221;][vc_column_text]<strong>mPrep CPD holder<\/strong>\u00a0for use with critical point dryers and some cryo-preparation applications<\/p>\n<p><b>Microwell plate covers <\/b>to cover and seal reagents in microwell plates<b>\u00a0<\/b>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner]\n\t\t\t\t            <\/div>\n\t        \t\t\t<\/dd><dt class=\"\">\n\t        \t<a class=\"ult-tabto-actitle withBorder ult_a \" id=\"1562004296515-2-615620146576341562081400189\" style=\"color:#74777b;border-color:#333333;;background-color:#e7ecea;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;\" href=\"#1562004296515-2-615620146576341562081400189\">\n\t        \t\t<i class=\"accordion-icon\"><\/i>\n\t        \t\t\t<span class=\"ult_tab_main ult_ac_main ult_noacordicnBoth\">\n\n\t\t\t\t\t\t<span  data-ultimate-target='#advanced-tabs-wrap-1370 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text no_icon ult_acordian-text ult-responsive\" style=\"font-weight:bold;;color:inherit \" >Applications<\/span>\n\t\t\t\t\t\t<\/span><\/a><\/dt>\n\t            \t\t<dd class=\"ult-tabto-accordionItem ult-tabto-accolapsed\">\n\t\t\t\t            <div class=\"ult-tabto-acontent\" style=\"color:#74777b;\">\n\t\t\t\t               [vc_empty_space height=&#8221;20px&#8221;][vc_column_text]<\/p>\n<h3>ASPs can be used for the full range of\u00a0specimen and grid preparation applications.\u00a0Please refer to TEM, SEM and vEM, and Materials Applications.<\/h3>\n<p>&nbsp;<\/p>\n<h3>See how the ASP-1000 and ASP-2000 have been used for these applications:<\/h3>\n<ul>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2017\/02\/AN601-Fast-Automated-Tissue-Processing-Kidney-with-ASP-1000.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Preparing kidney for TEM in 45 minutes from postfix to oven curing<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2019\/08\/Strader-automated_Prep_Core-Needle_Biopsy_Specimens_TEM_Microsc-Microanal-25-2019_AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Preparing core needle kidney biopsies for TEM including en bloc uranyl acid staining in 2 hours prior to resin curing<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2017\/04\/AN602-Automated-Prep-Muscle-ASP.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Processing oriented mammalian muscle for TEM in 2 hours from postfix to oven curing<\/a><\/li>\n<li>Serial block face specimen preparation of <a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2019\/08\/Goodman-Rapid_Auto_Prep_SBEM_Microsc-Microanal-25-2019_AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">brain<\/a>, <a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2019\/08\/Goodman-Postnatal_Hyperoxia_Cardiac_Muscle_3D_SEM_Automated_Prep_Micro-Microanal-25-2019-PDP-46_abstractposter.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">heart<\/a>, and <a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2019\/08\/McClain-Automated_Heavy_Metal_Tissue_Staining_Serial_Block_Face_Imaging_ASP-1000_Micro-Microanal-25-2019-PDP-52-Abstract.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">planeria <\/a>in about one day, instead of a week<\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2016\/08\/McClain-Bringing-Speed-Automation-Together-with-ASP-1000-Microsc-Microanal-22-2016-PDP-49-AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Rapid automated preparation of Planarian worm tissue for TEM in 3 hours<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2018\/08\/Marques-Optimization_automated_immuno_EM_pre_post_embedding_Micro-Microanal-24-2018_AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Fully automated immunogold pre-embedding and on grid labeling<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2017\/08\/Stewart-Preparing-LR-White-Embedded-Tissue-mPreps-Microsc-Microanal-23-2017-PDP-56-AbstractPoster.pdf\">Fixation and embedding in LR White resin in 45 minutes<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2017\/09\/AN-603-Rapid-Parallel-Liver-ASP.pdf\">Liver reliably and consistently prepared for TEM in just 133 minutes prior to resin curing<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2017\/08\/McClain-Rapid-Automated-enbloc-SEM-Microsc-Microanal-23-2017-PDP-59-AbstractPoster.pdf\">Planaria fixed, <em>en bloc<\/em> stained and ready for for 3D SEM block face imaging in 1.5 days<\/a><\/li>\n<li><a href=\"https:\/\/microscopyinnovations.com\/wp-content\/uploads\/2016\/08\/Vierrether-Nano-Particle-TEM-Sample-Prep-Primer-Microsc-Microanal-22-2016-1914-AbstractPoster.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Automated preparation of nano-particle TEM specimens.<\/a><\/li>\n<\/ul>\n<p>[\/vc_column_text]\n\t\t\t\t            <\/div>\n\t        \t\t\t<\/dd><dt class=\"\">\n\t        \t<a class=\"ult-tabto-actitle withBorder ult_a \" id=\"1562010045120-4-815620146576341562081400189\" style=\"color:#74777b;border-color:#333333;;background-color:#e7ecea;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;border-bottom-color:transparent;border-bottom-width:0px;border-bottom-style:solid;\" href=\"#1562010045120-4-815620146576341562081400189\">\n\t        \t\t<i class=\"accordion-icon\"><\/i>\n\t        \t\t\t<span class=\"ult_tab_main ult_ac_main ult_noacordicnBoth\">\n\n\t\t\t\t\t\t<span  data-ultimate-target='#advanced-tabs-wrap-1370 .ult-span-text'  data-responsive-json-new='{\"font-size\":\"desktop:15px;\",\"line-height\":\"\"}'  class=\"ult-span-text no_icon ult_acordian-text ult-responsive\" style=\"font-weight:bold;;color:inherit \" >Purchase<\/span>\n\t\t\t\t\t\t<\/span><\/a><\/dt>\n\t            \t\t<dd class=\"ult-tabto-accordionItem ult-tabto-accolapsed\">\n\t\t\t\t   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