Problems

Staining tissue sections on grids requires using fine forceps to transfer grids into grid boxes, onto stain droplets or staining apparatuses, back into grid boxes, and eventually onto the TEM stage. As a result, microscopists experience multiple challenges:

• Grids are easily damaged
• Handling grids is tedious
• Grids are easily lost or mixed up
• Difficulty achieving uniform staining times across multiple grids
• Stains exposed to air can be contaminated, precipitate, and evaporate

mPrep solutions

• Encapsulated grids reduce handling and damage.
• Grids may only be directly handled at the microtome and the microscope
• Grids in mPrep/g capsules are always labeled
• Simultaneous processing assures uniform timing
• Enclosed capsules reduce and can even eliminate air exposure

Learn more about staining tissue sections on TEM grids in the application notes below.